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Cardiovascular diseases (CVD) cause more deaths per year than the next six leading causes of death combined. There is also strong evidence for a role of oxidative stress, a key focus at Oxford Biomedical Research, in the development of CVD. Emerging risk factors for CVD include isoprostanes, C-reactive proteins, fibrinogen and plasminogen activator inhibitor 1 (PAI-1). Fibrinogen and PAI-1 are key components of the highly regulated coagulation process. Elevated PAI-1 transcription has been reported to be caused by oxidative stress activation of the AP-1 response element. Vascular endothelial cells also play a key role in cancer by limiting the access of circulating cells to sub-endothelial space and thereby reducing tumor metastasis.

We offer a wide range of antibodies, purified and recombinant proteins, and immunoassay kits for studies of proteins involved in cardiovascular biology – including those that play key roles in coagulation and its regulation, as well as other proteins that have been recognized as important in cardiovascular pathobiology.

Displaying 51 - 60 of 489
Product CAT.# Size Price
Anti Human Plasminogen MAb Sample Pack VA45 1 pack $560.00
Anti Human Plasminogen, Clone 13C3-B10 VA40 1.0 mg $645.00
Anti Human Plasminogen, Clone 1C10-F2 VA41 1.0 mg $645.00
Anti Human Plasminogen, Clone 2F6-C6 VA42 1.0 mg $645.00
Anti Human Plasminogen, Clone 4G6-B11 VA43 1.0 mg $645.00
Anti Human Plasminogen, Clone 9F9-C4 VA44 1.0 mg $645.00
Anti Human RAP, Biotin Labeled RA07 0.1 mg $330.00
Anti Human RAP, FITC Labeled RA04 0.1 mg $330.00
Anti Human tPA antiserum PA57 1.0 ml $475.00
Anti Human tPA IgG fraction PA59 1.0 mg $475.00