This antibody reacts with Prostacyclin Synthase from most mammals, including; bovine, mouse, rat, sheep, guinea pig and rabbit. It can be used for immunoassay, immunohistochemistry and immunoaffinity purification. Contents (per vial): 1 ml of culture medium from the isn-1 hybridoma cell line containing >20 µg of mouse IgG in 0.1% sodium azide.
Smith, W.L., DeWitt, D.L., and Allen, M.L. Bimodal Distribution of the PGI2 synthase antigen in smooth muscle cells. J. Biol. Chem. 258: 4922 (1983).
DeWitt, D.L., Day, J.S., Sonnenburg, W.K., and Smith, W.L. Concentrations of PGH Synthase and PGI2 Synthase in the Endothelium and Smooth Muscle of Bovine Aorta. J. Clin. Invest. 72: 1882 (1983).
DeWitt, D.L., and Smith, W.L. Purification of PGI2 Synthase by Immunoaffinity Chromatography: Evidence that the Enzyme is a Hemoprotein. J. Biol. Chem. 258: 3285 (1983).
DeWitt, D.L. and Smith W.L. Monoclonal Antibodies Against PGI2 Synthase: An Immunoradiometric Assay for Quantitating the Enzyme. Methods in Enzymology 86: 240 (1982).