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Cardiovascular diseases (CVD) cause more deaths per year than the next six leading causes of death combined. There is also strong evidence for a role of oxidative stress, a key focus at Oxford Biomedical Research, in the development of CVD. Emerging risk factors for CVD include isoprostanes, C-reactive proteins, fibrinogen and plasminogen activator inhibitor 1 (PAI-1). Fibrinogen and PAI-1 are key components of the highly regulated coagulation process. Elevated PAI-1 transcription has been reported to be caused by oxidative stress activation of the AP-1 response element. Vascular endothelial cells also play a key role in cancer by limiting the access of circulating cells to sub-endothelial space and thereby reducing tumor metastasis.

We offer a wide range of antibodies, purified and recombinant proteins, and immunoassay kits for studies of proteins involved in cardiovascular biology – including those that play key roles in coagulation and its regulation, as well as other proteins that have been recognized as important in cardiovascular pathobiology.

Displaying 141 - 150 of 489
Product CAT.# Size Price
Bovine Plasminogen PL24 1.0 mg $245.00
Bovine Vitronectin (multimeric) GP03 0.1 mg $270.00
Chicken Plasmin PL42 1.0 mg $405.00
Chicken Plasminogen PL40 1.0 mg $290.00
Dog Fibrinogen CT29 1.0 mg $165.00
Dog Prorenin, C-terminal 8x His tag RN30 0.1 mg $535.00
Dog Renin, C-terminal 8x His tag RN31 0.1 mg $535.00
Ecotin - Serine Protease Inhibitor RA11 1.0 mg $690.00
FITC Labeled Anti Human Renin RN13 1.0 mg $405.00
FITC Labeled anti Mouse factor IX CF20 1.0 mg $405.00