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Cardiovascular diseases (CVD) cause more deaths per year than the next six leading causes of death combined. There is also strong evidence for a role of oxidative stress, a key focus at Oxford Biomedical Research, in the development of CVD. Emerging risk factors for CVD include isoprostanes, C-reactive proteins, fibrinogen and plasminogen activator inhibitor 1 (PAI-1). Fibrinogen and PAI-1 are key components of the highly regulated coagulation process. Elevated PAI-1 transcription has been reported to be caused by oxidative stress activation of the AP-1 response element. Vascular endothelial cells also play a key role in cancer by limiting the access of circulating cells to sub-endothelial space and thereby reducing tumor metastasis.

We offer a wide range of antibodies, purified and recombinant proteins, and immunoassay kits for studies of proteins involved in cardiovascular biology – including those that play key roles in coagulation and its regulation, as well as other proteins that have been recognized as important in cardiovascular pathobiology.

Displaying 101 - 110 of 489
Product CAT.# Size Price
Anti Murine tPA PA62 1.0 mg $765.00
Anti Murine tPA PA63 1.0 mg $765.00
Anti Murine uPA PA71 1.0 mg $780.00
Anti Murine uPA (capture) PA70 1.0 mg $780.00
Anti Murine Vitronectin GP14 1.0 ml $395.00
Anti Murine Vitronectin IgG fraction GP16 1.0 mg $395.00
Anti PAI-1 (human, rat, rabbit, porcine) IgG Purified Monoclonal Antibody PI70 1.0 mg $530.00
Anti Plasminogen IgG/FITC Labeled PL65 1.0 mg $475.00
Anti Rabbit and Human PAI-1 Polyclonal Antibody PI71 1.0 mg $530.00
Anti Rat PAI-1 (inhibitory) Monoclonal Antibody PI65 1.0 mg $1,140.00