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Cardiovascular diseases (CVD) cause more deaths per year than the next six leading causes of death combined. There is also strong evidence for a role of oxidative stress, a key focus at Oxford Biomedical Research, in the development of CVD. Emerging risk factors for CVD include isoprostanes, C-reactive proteins, fibrinogen and plasminogen activator inhibitor 1 (PAI-1). Fibrinogen and PAI-1 are key components of the highly regulated coagulation process. Elevated PAI-1 transcription has been reported to be caused by oxidative stress activation of the AP-1 response element. Vascular endothelial cells also play a key role in cancer by limiting the access of circulating cells to sub-endothelial space and thereby reducing tumor metastasis.

We offer a wide range of antibodies, purified and recombinant proteins, and immunoassay kits for studies of proteins involved in cardiovascular biology – including those that play key roles in coagulation and its regulation, as well as other proteins that have been recognized as important in cardiovascular pathobiology.

Displaying 191 - 200 of 489
Product CAT.# Size Price
Human fibrinogen, plasminogen depleted CT13 25 mg $175.00
Human Fibronectin GP40 1.0 mg $220.00
Human Glu Plasminogen PL20 1.0 mg $245.00
Human Lys Plasmin PL22 1.0 mg $285.00
Human Neutrophil Elastase, Lyophilized SP34 0.5 mg $595.00
Human PAI-1 (Glycosylated - Active Form) PL76 0.5 mg $1,025.00
Human PAI-1 (Glycosylated - Latent Form) PL77 0.5 mg $1,025.00
Human PAI-1 (Glycosylated - Stable Mutant) PL75 0.5 mg $1,025.00
Human PAI-1 (6-X His Tag) PI06 0.5 mg $730.00
Human PAI-1 (active wild type) PI01 0.5 mg $730.00