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Cardiovascular diseases (CVD) cause more deaths per year than the next six leading causes of death combined. There is also strong evidence for a role of oxidative stress, a key focus at Oxford Biomedical Research, in the development of CVD. Emerging risk factors for CVD include isoprostanes, C-reactive proteins, fibrinogen and plasminogen activator inhibitor 1 (PAI-1). Fibrinogen and PAI-1 are key components of the highly regulated coagulation process. Elevated PAI-1 transcription has been reported to be caused by oxidative stress activation of the AP-1 response element. Vascular endothelial cells also play a key role in cancer by limiting the access of circulating cells to sub-endothelial space and thereby reducing tumor metastasis.

We offer a wide range of antibodies, purified and recombinant proteins, and immunoassay kits for studies of proteins involved in cardiovascular biology – including those that play key roles in coagulation and its regulation, as well as other proteins that have been recognized as important in cardiovascular pathobiology.

Displaying 1 - 10 of 490
Product CAT.# Size Price
Ac-TVASSSTA Octapeptide PI14 5.0 mg $515.00
Active Human PAI-1 functional assay kit PI90 Kit $505.00
Active Human uPA Functional Assay Kit PL91 Kit $505.00
Active Mouse tPA (recombinant) PA56 0.1 mg $350.00
Active mouse uPA Functional Assay Kit PL92 Kit $525.00
Active Mouse Urokinase, Alexa Fluor 700 Labeled VA56 0.05 mg $525.00
Active Murine PAI-1 functional assay kit PI91 Kit $505.00
Active Pig PAI-1 Functional Assay Kit PI95 Kit $505.00
Active porcine tPA functional assay UP60 Kit $520.00
Active porcine tPA, recombinant UP59 0.1 mg $350.00