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Cardiovascular diseases (CVD) cause more deaths per year than the next six leading causes of death combined. There is also strong evidence for a role of oxidative stress, a key focus at Oxford Biomedical Research, in the development of CVD. Emerging risk factors for CVD include isoprostanes, C-reactive proteins, fibrinogen and plasminogen activator inhibitor 1 (PAI-1). Fibrinogen and PAI-1 are key components of the highly regulated coagulation process. Elevated PAI-1 transcription has been reported to be caused by oxidative stress activation of the AP-1 response element. Vascular endothelial cells also play a key role in cancer by limiting the access of circulating cells to sub-endothelial space and thereby reducing tumor metastasis.

We offer a wide range of antibodies, purified and recombinant proteins, and immunoassay kits for studies of proteins involved in cardiovascular biology – including those that play key roles in coagulation and its regulation, as well as other proteins that have been recognized as important in cardiovascular pathobiology.

Displaying 241 - 250 of 489
Product CAT.# Size Price
Human Renin/Prorenin double Depleted Plasma RN32 10.0 ml $345.00
Human sc-tPA, ATA-FPR-CMK inactivated PA42 0.1 mg $465.00
Human tPA (>85% single chain FITC Label) PA52 0.1 mg $485.00
Human tPA (>85% single chain) PA51 0.1 mg $255.00
Human tPA (>95% two chain) PA54 0.1 mg $375.00
Human tPA Activity ELISA Kit PA90 Kit $520.00
Human tPA Depleted Plasma (Na Citrate) PA43 10 mL $335.00
Human tPA total antigen ELISA Kit PA91 Kit $520.00
Human tPA, Immobilized PA48 1.0 ml $630.00
Human tPA, Non-cleavable PA49 0.1 mg $375.00